Head & Neck Skin Cancer

Merkel cell carcinoma (MCC) is a rare but aggressive type of skin cancer that originates from Merkel cells, which are found in the skin's top layer. Merkel cells are involved in the sense of touch. It presents on sun-exposed areas of the head and neck, appearing as firm, painless nodules that may be red, violet or skin-coloured.

While aging and fair complexion may contribute to the carcinoma, in about 80% of the cases, MCC is associated with infection by the Merkel Cell Polyomavirus (MCV). The virus integrates into the cancer cells' DNA, potentially contributing to tumour formation. Individuals with weakened immune systems due to conditions like HIV/AIDS or organ transplantation have a higher risk of developing MCC.